222 Fifth
Seattle, Washington

A New Beacon of Innovation for Seattle

Located in the heart of Seattle’s innovation cluster, 222 Fifth is a state-of-the-art life science research facility and modern workplace that adapts to the evolving needs of the industry and surrounding community.
HIGHLIGHTS
  • 9-Stories, 200,000-Square-Feet
  • 100% Electric
  • Offset Massing and Dynamic Shifting Volumes
  • Interconnecting Stairs Act as a Vertical Ribbon of Circulation
  • Three Tenant-Ready Speculative Lab Floors
  • Multiple Roof Decks Offering Expansive Outdoor Spaces With Panoramic Views
  • Performs 25% Better Than the 2015 Seattle Energy Code Requirements
A building with glass walls.
Challenge

Driven by rapid advances in medicine and technology, the life sciences market is going through a period of accelerated innovation — one that is having a significant impact on company culture and the physical workplace itself. Design solutions are far more bold than they used to be. Healthy, vibrant, and resilient spaces have become a priority because they help organizations stay agile, effective, and competitive in a fast-changing landscape.

Solution

222 Fifth is an R&D hub purpose-built for flexibility, tenant engagement, and long-term sustainability. Designed to meet the evolving needs of the life sciences industry, the building’s offset massing and dynamic volumes establish a striking identity. A bold feature stair drives vertical connectivity and movement, while terraces and a rooftop deck provide outdoor spaces with expansive views. Balancing work and research, 222 Fifth cultivates collaboration and continuously adapts to the shifting priorities of tenants and the surrounding community.

Impact

Sustainability is at the forefront of 222 Fifth’s design. The building performs 25% better than the 2015 Seattle Energy Code requirements, achieving enhanced energy efficiency through high-performance glazing and 100% electrified building systems including chilled beams and heat recovery HVAC. These sustainable features not only reduce environmental impact but also earned the building additional floor area through the Green Building Standard incentive program, ensuring long-term value for tenants and the surrounding community.

A group of people walking inside a building.
People sitting in chairs in a room.
A group of people in lab coats.
By combining world-class facilities with a prime location and forward-thinking initiatives like CoLabs, 222 Fifth is set to play a pivotal role in supporting Seattle’s growing life science ecosystem.
—Uly Rivera, Co-Labs Director with Lincoln Property Company
A tall tower in a city.
A man and woman walking up a red staircase.
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A low angle view of a building.
A building with a glass front.
A large building with a street in front of it.
A building with a city in the background.
A city skyline at night.
A city with a tall tower.
© Video and Images by Heywood Chan
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